Responsible living labs: what can go wrong?
This study aims to investigate how living lab (LL) activities align with responsible research and innovation (RRI) principles, particularly in artificial intelligence (AI)-driven digital transformation (DT) processes. The study seeks to define a framework termed “responsible living lab” (RLL), emphasizing transparency, stakeholder engagement, ethics and sustainability. This emerging issue paper also proposes several directions for future researchers in the field.
Read more on Emerald!
Expression of CD83 in tissue-resident regulatory T cells maintains local homeostasis and restricts effector cells in allergic asthma
Non-lymphoid tissue Tregs (NLT-Tregs) are critical for tissue homeostasis, inflammation control, and induction of mucosal repair. Recent single-cell RNA sequencing data identified expression of CD83 as part of a NLT-Treg signature, however its biological significance for this specialized Tregs was not yet fully understood. In our previous investigations, we found …
Read more on Research Square!
Poly I:C Pre-Treatment Induced the Anti-Viral Interferon Response in Airway Epithelial Cells
Type I and III interferons are among the most important antiviral mediators. Increased susceptibility to infections has been described as being associated with impaired interferon response in asthmatic patients. In this work, we focused on the modulation of interferon dysfunction after the rhinovirus infection of airway epithelial cells…
Read more on Viruses!
HealthAir: A Crowdsourcing mHealth Platform for Air Pollution Effects on Citizens Health Status
Crowdsourcing systems offer numerous advantages for acquiring data, which can contribute to the development of modern concepts such as Smart Cities. Air quality in urban areas has been identified as a crucial theme and requirement, towards ideal city of the future that can be adapted upon its citizens’ needs and comfort. Thus, besides the sensing infrastructure, a complementary system must be […]
Read more on IEEE Xplore!
(POSTER) A Holistic IoT-Enabled Approach for Indoor Air Quality Control
Indoor air quality (IAQ) is an important yet often overlooked aspect of public health, with poor IAQ contributing to a significant number of diverse health problems worldwide. Existing air quality standards have failed to fully address the problem, however emerging technologies in the field of IoT have demonstrated promise in effectively addressing this issue. This concept paper advocates a hybrid hierarchy system for IAQ monitoring that incorporates both offline and online connectivity. The system utilizes sensing elements that can perform a wide range of functions, including autocalibration, pollution event detection, and more, autonomously from the network. By combining a gateway device, the system’s capabilities are …
Read more on IEEE Xplore!
Addressing adverse synergies between chemical and biological pollutants at schools – The ‘SynAir-G’ hypothesis
While the number and types of indoor air pollutants is rising, much is suspected but little is known about the impact of their potentially synergistic interactions, upon human health. Gases, particulate matter, organic compounds but also allergens and viruses, fall within the ‘pollutant’ definition. Distinct populations, such as children and allergy and asthma sufferers are highly susceptible, while a low socioeconomic background is a further susceptibility factor; however, […]
Now available on Allergy!
Theorizing Living Lab research: The way forward
Living Labs have become a popular approach to facilitate multi-stakeholder engagement in open innovation processes in real-life settings. Despite their extensive application across various research fields, there is still a lack of theoretical understanding in this area. This study aims to take the first step towards developing a theory for Living Labs. In doing so, we will […]
Read more on DiVA!
Field calibration of a low-cost air quality monitoring device in an urban background site using machine learning models
Field calibration of low-cost air quality (AQ) monitoring sensors is essential for their successful operation. Low-cost sensors often exhibit non-linear responses to air pollutants and their signals may be affected by the presence of multiple compounds making their calibration challenging. We investigate different approaches for the field calibration of an AQ monitoring device named ENSENSIA, developed in the Institute of Chemical Engineering Sciences in Greece. The present study focuses […]
Read more on Atmosphere!
Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
Asthma is a chronic airway disease whose exacerbations are often triggered by rhinovirus infection. TGF-β1 induces rhinovirus replication in infected cells. Moreover, TGF-β1 is a pleiotropic mediator that is produced by many immune cells in the latent, inactive form bound to the latency-associated peptide (LAP) and to the transmembrane protein glycoprotein A repetitions predominant (GARP). In this study we wanted to investigate the effect […]
Read more on Cells!
Roadmap and Guidelines
SynAir-G Roadmap and Guidelines will be developed by consolidating the outcomes and lessons learned from research and piloting activities. The Roadmap will be a comprehensive report including training material, published as a white paper with recommendations to authorities, EU policymakers, and the industry. The report will include a compilation of policies, standards, and technologies used in SynAir-G and a selection of best practices. Guidelines will also target healthcare professionals caring for children with allergy & asthma, sensitizing them to the potential risks of indoor air pollution, the synergies with chemical and biological triggers, and potential mitigation measures.
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