This paper examines whether 4-Octyl Itaconate can reduce oxidative stress caused by diesel exhaust particles in human nasal cells and PBMCs. Exposure to diesel particles increased oxidative stress and inflammation, while 4-Octyl Itaconate lowered ROS levels and boosted antioxidant genes via NRF2 activation. These results suggest 4-Octyl Itaconate helps protect cells from diesel-induced damage through […]